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Results for "

glutaminyl cyclase

" in MedChemExpress (MCE) Product Catalog:

7

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2

Recombinant Proteins

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  • HY-P71670
    QPCT Protein, Mouse (HEK293, His)

    Qpct; glutaminyl-peptide cyclotransferase; EC 2.3.2.5; glutaminyl cyclase; QC; glutaminyl-tRNA cyclotransferase

    		 Mouse HEK293
    The QPCT protein plays a key role in pyroglutamyl peptide biosynthesis and exhibits substrate preference for N-terminal glutamine residues while showing specificity for residues near the N-terminus. Notably, its catalytic activity is independent of chain length beyond the second residue, emphasizing the importance of QPCT in the precise biosynthesis of pyroglutamyl peptides with diverse N-termini, contributing to various biological background. QPCT Protein, Mouse (HEK293, His) is the recombinant mouse-derived QPCT protein, expressed by HEK293 , with N-His, N-Myc labeled tag. The total length of QPCT Protein, Mouse (HEK293, His) is 327 a.a., with molecular weight of ~41.6 kDa.
  • HY-P76560
    QPCT Protein, Human (sf9, His)

    glutaminyl-peptide cyclotransferase; QC; Glutamyl cyclase; EC

    		 Human Sf9 insect cells
    QPCT Protein synthesizes pyroglutamyl peptides, favoring N-terminal glutaminyl residue over adjacent acidic and tryptophan residues. It catalyzes N-terminal pyroglutamate formation, particularly [Glu-3]-amyloid-beta in APP peptides. In lab settings, it aids pyroglutamate formation in truncated amyloid-beta peptides. QPCT Protein may contribute to N-terminal pyroglutamate formation in peptides linked to amyloid-related plaque development. QPCT Protein, Human (sf9, His) is the recombinant human-derived QPCT protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of QPCT Protein, Human (sf9, His) is 329 a.a., with molecular weight of ~38 kDa.

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